SUMO1-conjugation is altered during normal aging but not by increased amyloid burden
نویسندگان
چکیده
منابع مشابه
Altered synaptic dynamics during normal brain aging.
What is the neuroanatomical basis for the decline in brain function that occurs during normal aging? Previous postmortem studies have blamed it on a reduction in spine density, though results remain controversial and spine dynamics were not assessed. We used chronic in vivo two-photon imaging of dendritic spines and axonal boutons in somatosensory cortex for up to 1 year in thy1 GFP mice to tes...
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متن کاملCommentary: Analysis of SUMO1-conjugation at synapses
Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, IPMC, Université Côte d’Azur, Nice, France, 3 Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland, 4 Taub Institute and Department of Pathology and Cell Biology, Columbia University, New York, NY, United States, 5 Department of Applied Sciences, University of the West of England, B...
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ژورنال
عنوان ژورنال: Aging Cell
سال: 2018
ISSN: 1474-9718
DOI: 10.1111/acel.12760